Progeria_Eveland

PROGERIA [] -considered an autosomal dominant condition -results from new mutations in the LMNA gene -almost always occurs in people with no history of the disease in their family -a genetic condition causing excessive aging in childhood

SYMPTOMS [] Signs and symptoms of this progressive disorder include:
 * Slowed growth, with below-average height and weight
 * A narrowed face and beaked nose
 * Hair loss (alopecia), including eyelashes and eyebrows
 * Hardening and tightening of skin on trunk and extremities (scleroderma)
 * Head disproportionately large for face
 * Thin lips
 * Visible veins
 * Prominent eyes
 * Small lower jaw (micrognathia)
 * High-pitched voice
 * Delayed and abnormal tooth formation
 * Diminished body fat and muscle
 * Stiff joints
 * Hip dislocation
 * Insulin resistance
 * Irregular heartbeat

TREATMENT OPTIONS []
 * **Low-dose aspirin.** A daily dose may help prevent heart attacks and stroke.
 * **Other medications.** Depending on your child's condition, your doctor may prescribe other medications, such as statins to lower cholesterol or anticoagulants to help prevent blood clots. The use of growth hormone may help increase height and weight.
 * **Physical and occupational therapy.** These may help with joint stiffness and hip problems and may allow your child to remain active.
 * **Extraction of primary teeth.** Your child's permanent teeth may start coming in before his or her baby teeth fall out. Extraction may help prevent problems associated with the delayed loss of baby teeth, including overcrowding and developing a second row of teeth when permanent teeth come in